Laser-Assisted Drug Delivery (LADD)

Enhancing Skin Treatment Through Precision and Science

Laser-Assisted Drug Delivery (LADD) is an advanced dermatologic technique that allows therapeutic agents to penetrate the skin more effectively by using laser technology to temporarily enhance absorption. At Skinfocused Dermatology, LADD is used as a strategic medical tool as part of a meticulously crafted, physician-designed treatment plan to improve skin quality, tone, and long-term health.

Rather than relying on topical application alone, LADD enables us to deliver selected medications and biologic agents to the layers of skin where they can have the greatest clinical impact.

How Laser-Assisted Drug Delivery Works

Using non-ablative and fractional lasers, we create microscopic, evenly spaced channels in the skin. These micro-channels are open only temporarily and close naturally as the skin heals. The physicians harness this clinical finding for the efficient and effective localized treatment of various conditions. Immediately after the laser treatment, physician-selected agents are applied. The laser-created channels allow these compounds to bypass the skin’s outer barrier and penetrate more efficiently and uniformly.

Laser primes the skin →

targeted agents reach deeper layers →

results are enhanced.

Why Laser-Assisted Delivery Matters

The skin’s barrier is essential—but it also limits how much of a topical treatment can truly reach its target. LADD allows us to:

• Improve penetration and bioavailability of active ingredients

• Achieve more consistent and predictable outcomes

• Use lower concentrations more effectively

• Customize therapy to specific concerns and skin types

This makes LADD especially valuable for patients seeking measurable improvement in skin quality, not just surface-level enhancement.

Physician-Selected Agents Used with LADD

At Skinfocused, the choice of medication or biologic is always individualized. Commonly utilized agents include:

Biostimulatory Compounds

Biostimulatory materials related to poly-L-lactic acid—the same collagen-stimulating technology used in injectable treatments like Sculptra—may be incorporated in laser-assisted protocols when appropriate. Delivered through the skin rather than injected, these compounds support collagen signaling, dermal strength, and long-term skin quality.

Platelet-Rich Plasma (PRP)

PRP is derived from the patient’s own blood and contains growth factors that support healing and regeneration. When paired with laser-assisted delivery, PRP can:

• Enhance recovery

• Improve texture and luminosity

• Support collagen remodeling

• Strengthen compromised or aging skin

This is a powerful option for patients seeking a biologic, regenerative approach.

Tranexamic Acid

Tranexamic acid is frequently used to address pigmentation disorders, including melasma and uneven tone. When delivered via laser-assisted pathways, it allows for:

• More effective penetration

• Targeted pigment modulation

• Reduced reliance on higher-strength topical regimens

This approach is particularly helpful for patients with recurrent or treatment-resistant pigmentation concerns.

Other Targeted Therapeutics

Depending on skin needs, additional brightening agents, anti-inflammatory compounds, or barrier-supporting formulations may be used. Selection is always guided by physician assessment and safety considerations.

Elevated Delivery. Intelligent Results.

Laser-Assisted Drug Delivery reflects Skinfocused’s philosophy:precision over excess, strategy over trend, and long-term skin health over quick fixes